By Hugo Francisco de Souza Reviewed by Susha Cheriyedath, M.Sc. Jul 10 2025 New research reveals that while losing weight can rejuvenate aging fat tissue, stubborn immune cells keep a “memory” of obesity, offering fresh targets for lasting metabolic health. Study: Selective remodelling of the adipose niche in obesity and weight loss . Image Credit: Andrey_Popov / Shutterstock In a recent study published in the journal  Nature , researchers utilized next-generation assays to investigate the