University of California - San Francisco Aug 11 2025 A new generation of malaria drugs failed clinical trials, in part because they were hard to swallow. UCSF chemists remodeled their structures to make them more soluble, while maintaining their effectiveness against drug-resistant parasites. The search for new ways to treat malaria - a disease that kills some 600,000 people a year, most of them children in Sub-Saharan Africa - may have just gotten a boost. Chemists at UC San Francisco have