Researchers uncover the potential of JAK inhibitors to treat life-threatening skin disease

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By Dr. Sushama R. Chaphalkar, PhD. Reviewed by Susha Cheriyedath, M.Sc. Oct 17 2024 Leveraging advanced spatial proteomics, scientists have identified the JAK/STAT pathway as a critical target for treating toxic epidermal necrolysis, offering new hope for patients with this life-threatening skin disease. Disease course in a patient with TEN (SCORTEN 4) associated with cancer treatment. Disease progression was observed during high-dose intravenous methylprednisolone treatment and the patient

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