Bills’ James Cook Sits Out Wednesday Practice, Game Availability Unclear

Ana Maria Rus

Getty Buffalo Bills running back, James Cook, scoring a touchdown in the third quarter against the Carolina Panthers on October 26, 2025. The Bills are riding high after beating the Kansas City Chiefs 28-21 on Sunday. One of the reasons why Buffalo was able to pull off the win was due to running back James Cook . Cook carried the ball 27 times for 114 yards and, although he didn’t find the end zone, he allowed his teammates, running back Ty Johnson and quarterback Josh Allen , to run in a few

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