Hormone-driven immune cells may explain sex differences in chronic pain
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Michigan State University Feb 22 2026 Chronic pain lasts longer for women than men, and new research suggests differences in hormone-regulated immune cells, called monocytes, may help explain why. In a new paper in Science Immunology , researchers at Michigan State University found a subset of monocytes release a molecule to switch off pain. These cells are more active in males due to higher levels of sex hormones such as testosterone, the team found. Females, however, experienced longer-
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