Cancer-linked mutations in the brain cells may drive Alzheimer’s disease
Andreea Neblea
Boston Children's Hospital Apr 21 2026 As the body ages, cells naturally accumulate dozens of genetic mutations each year. New research from Boston Children's Hospital, published in Cell , finds that the brain's resident immune cells, microglia, amass mutations in specific cancer-driving genes yet they don't manifest as cancer. Instead, these mutations may help drive Alzheimer's disease. The research team, led by Christopher Walsh, MD, PhD, Chief of the Division of Genetics and Genomics at
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