TMEM219 inhibition shows promise in restoring intestinal health in IBD
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Boston Children's Hospital May 15 2025 An international study led by Paolo Fiorina from Boston Children's Hospital and in collaboration with researchers from University of Milan highlights the beneficial effect of inhibiting the death receptor TMEM219 to restore mucosal healing in inflammatory bowel diseases. Findings were published today in the Journal of Clinical Investigation. Fiorina and colleagues demonstrated that the pharmacological blockade of TMEM219 signal through a recombinant
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