By Tarun Sai Lomte Reviewed by Susha Cheriyedath, M.Sc. Sep 11 2025 A citrus-derived flavonoid shows potent antioxidant and anti-inflammatory effects in immune cells, hinting at future therapeutic potential. Study: Exploring the In Vitro Anti-Inflammatory Effect of Citrus Fruit Hesperidin Supplementation . Image Credit: kisa2014 / Shutterstock In a recent study published in the  Food Science & Nutrition journal, researchers explored the anti-inflammatory and antioxidant effects of hesperidin.