Chinese Academy of Sciences May 11 2025 Oral squamous cell carcinoma (OSCC) is a leading cause of cancer-related deaths, and early detection is key to improving patient outcomes. However, the mechanisms driving the transition from preneoplastic lesions to full-blown cancer are not well understood. Previous research has primarily targeted advanced OSCC, overlooking the early stages of tumor progression. The new study focuses on lysine-specific demethylase 1 (LSD1), an epigenetic regulator that