By Dr. Priyom Bose, Ph.D. Reviewed by Lauren Hardaker Sep 11 2025 A yearlong phase 3 trial shows elinzanetant can cut hot flashes by nearly three-quarters while maintaining a strong safety profile, positioning it as a promising new option for women seeking alternatives to hormone therapy. Study: Elinzanetant for the Treatment of Vasomotor Symptoms Associated With Menopause . Image credit: New Africa/Shutterstock.com A recent study in JAMA Internal Medicine investigated the safety and efficacy