A charity with a presence on hundreds of UK high streets is closing 190 stores. Cancer Research UK has blamed rising costs and changing shopping habits for the closures. The charity has already closed several of its shops, with dozens more set to disappear from the high street by 2027. It has been a fixture of the high street since its first shop opened in 1982. The initial wave of 90 shop shut-downs is due to be completed by the end of this month, with Cancer Research UK saying a further 100