Ruhr University Bochum Oct 28 2025 Microcephaly is a congenital malformation that leads to a significantly reduced brain size and is often accompanied by developmental delay. An international research team led by Dr. Tran Tuoc from the Department of Human Genetics at Ruhr University Bochum, Germany, has discovered a previously unknown genetic cause for this condition. Mutations in the EXOSC10 gene - a central component of the RNA degradation complex ("exosome") - cause primary microcephaly. The