Semi-synthetic bile acid could be a promising therapeutic option for TH17-mediated intestinal diseases
Cătălin Roșioru
Medical University of Vienna Mar 14 2025 A research team from the Medical University of Vienna has made further progress in the treatment of intestinal inflammation. A study shows that the semi-synthetic bile acid NorUDCA inhibits in the intestine the formation of pro-inflammatory T helper 17 cells (T H 17) and at the same time promotes the generation of anti-inflammatory regulatory T cells. This could be a promising new therapeutic option for patients with T H 17-mediated intestinal diseases.
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