University of Delaware Jul 11 2025 One in three adults in the U.S. has three or more risk factors for a newly recognized but increasingly common condition: cardiovascular-kidney-metabolic (CKM) syndrome. First recognized by the American Heart Association (AHA) in a 2023 presidential advisory, CKM connects heart and metabolic health with kidney function as intertwined drivers of cardiovascular disease (CVD).  Long before CKM was defined, millions of Americans were unknowingly progressing through