By Vijay Kumar Malesu Reviewed by Susha Cheriyedath, M.Sc. Nov 6 2025 Scientists have uncovered a microglial switch that transforms these immune cells from plaque-promoting to plaque-protective, offering a new path toward immunomodulatory treatments for Alzheimer’s disease. Study: Lymphoid gene expression supports neuroprotective microglia function . Image Credit: sfam_photo / Shutterstock In a recent study published in the journal  Nature , researchers investigated how lowering the