Engineered biomaterial promotes formation of cancer-fighting immune cell clusters

Cristiana Gigina

H. Lee Moffitt Cancer Center & Research Institute Nov 6 2025 Researchers at Moffitt Cancer Center have developed a novel biomaterial-based system that induces the formation of tertiary lymphoid-like structures, or TLSs. These immune cell clusters are increasingly linked to improved outcomes and treatment responses in cancer. Results of their study was published in the Proceedings of the National Academy of Sciences.  TLSs are specialized immune structures that sometimes form within tumors,

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