Veterans Health Service Medical Center, Korea May 10 2025 Background:  Krebs von den Lungen-6 (KL-6), predominantly expressed by type II alveolar cells, is linked to the prognosis and severity of interstitial lung disease (ILD). This investigation sought to explore the relationship between KL-6 concentrations and the presence of ILD versus interstitial lung abnormalities (ILA). Methods:  This single-center retrospective study included 147 patients who were suspected of ILD and underwent KL-6