Sichuan University Mar 10 2026 Dental pulp injury caused by trauma or deep caries often leads to inflammation, tissue necrosis, and eventual loss of tooth vitality. In severe cases, bacterial invasion and sustained immune responses further compromise the pulp's microenvironment, disrupting its natural capacity for repair. Although regenerative endodontic approaches aim to restore living tissue, predictable biological repair remains difficult to achieve. Central to successful regeneration is the