In this talk, Dr. Greg Worrell explores how epilepsy serves as a powerful model for advancing brain‑computer interfaces, neuromodulation, and circuit‑level therapies. He explains why epilepsy’s unpredictability, broad comorbidities, and poor patient self‑reporting make it an ideal test bed for developing next‑generation sensing and stimulation systems. Dr. Worrell traces two decades of innovation—from early seizure‑forecasting implants to advanced bidirectional devices that record brain