Frontiers Journals Oct 10 2025 Hypertrophic cardiomyopathy (HCM), a common genetic heart disorder, is often caused by mutations in sarcomere-related genes. While extensively studied in European populations, its genetic basis in Chinese individuals remains poorly understood. In a groundbreaking cross-sectional study, researchers from West China Hospital and the University of Birmingham analyzed whole-exome sequencing data from 593 Chinese and 1,232 UK HCM patients, along with controls. They