Lipid accumulation in tumors linked to therapy resistance in breast cancer
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Baylor College of Medicine Mar 28 2025 A new study published in the journal Immunity reveals a mechanism that allows triple negative breast cancer (TNBC) to develop resistance to therapy. Researchers at Baylor College of Medicine showed that lipid accumulation in tumor cells and nearby immune cells promotes immune suppression, but disrupting lipid formulation reverses treatment resistance and the immunosuppressive microenvironment. Standard-of-care treatment for TNBC includes chemotherapy and
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