Compuscript Ltd Mar 28 2025 Iridocorneal endothelial (ICE) syndrome is a rare, irreversibly blinding ocular disorder with an unknown etiology. Lack of targeted effective drugs, inadequate disease prognosis, and high relapse rates post-surgery are the current challenges of ICE. Therefore, understanding its genomic and epigenomic landscape could aid in developing etiology-based therapies. This research, published in the Genes & Diseases journal by a team from Sun Yat-sen University, Guangzhou