Science and Technology Review Publishing House Oct 10 2025 Recently, a research team led by Professor Jian-Xun Wang and Professor Tao Yu from Qingdao University made a significant breakthrough in understanding the role of lactylation modification in aortic dissection (AD). Their study revealed that lactylation of the mitochondrial ATP synthase subunit alpha (ATP5F1A) at the K531 site promotes the development and progression of AD by impairing mitochondrial function and inducing a phenotypic