Science and Technology Review Publishing House Mar 9 2026 Immunome (immune cells and functions) variations are closely related to human health. Various exposures, including the external environment and personal lifestyles, are important factors affecting the immune system. Recent advances in research have focused on immune system variation mainly from a genome perspective. This population-based study (N=1,001 from The Human Phenome Atlas (THPA) cohort) investigated the immune variability from