International Society for Stem Cell Research Nov 6 2025 Type 1 diabetes is caused by an insufficient production of the hormone insulin by cells in the pancreas called beta cells and estimated to affect 9.5 million people worldwide. Low insulin levels allow glucose levels to remain elevated, which in the long term can damage organs such as the kidneys, the eyes, and the cardiovascular system. People with diabetes require lifelong monitoring of blood sugar levels coupled with insulin injections