Compuscript Ltd Sep 11 2025 Primary liver cancer is the third leading cause of cancer-related deaths, of which hepatocellular carcinoma (HCC) accounts for approximately 90% of all liver cancer cases. Given that the development of HCC is a multifactorial and multistage process, its increasing incidence underscores the need to understand its molecular mechanisms and identify potential biomarkers and therapeutic targets. Previous studies have implicated chromosome 1 open reading frame 122 (