Mass General Brigham Nov 3 2025 Increasing your steps by even a little bit may help slow down the progression of Alzheimer's disease among people at heightened risk, according to a new study. In a paper published in  Nature Medicine , Mass General Brigham researchers found that physical activity was associated with slower rates of cognitive decline in older adults with elevated levels of amyloid-beta, a protein associated with Alzheimer's. Cognitive decline was delayed by three years on average