New therapeutic target overcomes ovarian cancer immunotherapy resistance

Dariana Florescu

The Mount Sinai Hospital / Mount Sinai School of Medicine Nov 1 2024 Researchers at the Icahn School of Medicine at Mount Sinai have discovered a way that ovarian cancer tumors manipulate their environment to resist immunotherapy and identified a drug target that could overcome that resistance. The study, published in the October 30 online issue of  Cell , used a cutting-edge spatial genomics technology and preclinical animal models, with tumor specimens from ovarian cancer patients further