Education Menopause involves the permanent stopping of menstruation . There is a distinct drop in estrogen that occurs in menopause. Hormone therapy can help minimize certain menopause symptoms like hot flashes and vaginal dryness . Experts are interested in determining the full benefits of menopausal hormone therapy as well as the potential drawbacks. A paper recently published in PLOS Medicine reported data from the Kronos Early Estrogen Prevention Study (KEEPS) Continuation study.