Education Past studies show that getting enough physical activity can help lower a person’s risk for major adverse cardiovascular events (MACE) , such as heart failure , stroke, and heart attack . “Physical inactivity is a major public health issue contributing to [up to] 6 million deaths per year globally, and is directly responsible for at least 15–20% of cardiovascular disease,” Emmanuel Stamatakis, PhD , director of the Mackenzie Wearables Research Hub in the Charles Perkins Centre, and