By Dr. Sanchari Sinha Dutta, Ph.D. Reviewed by Lauren Hardaker Jan 18 2026 A decades-long study shows how patterns in circulating metabolites, shaped by genes and lifestyle, can identify people at high risk of type 2 diabetes well before symptoms emerge. Study: Circulating metabolites, genetics and lifestyle factors in relation to future risk of type 2 diabetes . Image Credit: Halfpoint / Shutterstock Researchers from Mass General Brigham and Albert Einstein College of Medicine have discovered