Multicolor electron microscopy reveals proteins and cell architecture at nanoscale resolution

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Biophysical Society Feb 22 2026 Scientists have developed a new imaging technique that uses a novel contrast mechanism in bioimaging to merge the strengths of two powerful microscopy methods, allowing researchers to see both the intricate architecture of cells and the specific locations of proteins-all in vivid color and at nanometer resolution. The breakthrough, called multicolor electron microscopy, addresses a longstanding challenge in biological imaging: scientists have traditionally had to