By Chad de Guzman March 3, 2025 5:00 AM EST G oing into the 2025 Academy Awards , Demi Moore had become a favorite for the Best Actress category. The 62-year-old’s portrayal of an aging, insecure actress deemed past her prime who took a black-market drug to try to become a “younger, more beautiful, more perfect” version of herself in the body horror The Substance earned her Best Actress accolades at the Golden Globe Awards, Critics Choice Awards, and Screen Actors Guild Awards. But it wasn’t