U.S. Food and Drug Administration Feb 28 2025 Grapefruit juice and grapefruit can be part of a healthy diet. Grapefruit has vitamin C and potassium, nutrients your body needs to work properly. Grapefruit juice and grapefruit can affect the way your medicines work, and that food and drug interaction can be a concern. The U.S. Food and Drug Administration has required that some prescription and over-the-counter drugs generally taken by mouth include warnings against drinking grapefruit juice or