Monash University Nov 27 2024 Effective immunity hinges on the ability to sense infection and cellular transformation. In humans, there is a specialized molecule on the surface of cells termed MR1. MR1 allows sensing of certain small molecule metabolites derived from cellular and microbial sources; however, the breadth of metabolite sensing is unclear. Published in PNAS , researchers at the Monash University Biomedicine Discovery Institute have identified a form of Vitamin B6 bound to MR1 as a