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Study finds no evidence linking sickle cell trait to sudden death

Flavius Niculescu

American Society of Hematology Jan 31 2025 A systematic literature review found no evidence to support that physical exertion without rhabdomyolysis (muscle breakdown) or heat injury can cause sudden death for individuals with sickle cell trait (SCT), nor is there any high-level evidence that SCT causes acute pain crises. These results were published today in the American Society of Hematology's flagship journal, Blood, and informed the Society's updated position statement on SCT.  "SCT has

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