Massachusetts Institute of Technology Sep 10 2025 A new study from MIT neuroscientists reveals how rare variants of a gene called ABCA7 may contribute to the development of Alzheimer's in some of the people who carry it. Dysfunctional versions of the ABCA7 gene, which are found in a very small proportion of the population, contribute strongly to Alzheimer's risk. In the new study, the researchers discovered that these mutations can disrupt the metabolism of lipids that play an important role in