By Vijay Kumar Malesu Reviewed by Susha Cheriyedath, M.Sc. Apr 2 2026 A major genetic study has uncovered a surprisingly common recessive cause of neurodevelopmental disorder, revealing how hidden changes in a small RNA gene can disrupt brain development and open new paths for diagnosis and family counseling. Study: Biallelic variants in RNU2-2 cause the most prevalent known recessive neurodevelopmental disorder . Image Credit: Lightspring / Shutterstock In a recent study published in  Nature