We, the Leaders of the Group of Seven (G7), affirm our joint effort to fight the production, distribution, and sale of illicit synthetic drugs, and the criminal networks which traffic these drugs, which collectively impact the health, security, and well-being of our citizens and of people around the world. Such drugs, especially synthetic opioids such as fentanyl, its analogues and nitazenes, represent an escalating and critical public health emergency, resulting in hundreds of thousands of