WASHINGTON (AP) — When the week began, several senior positions at the U.S. Department of Health and Human Services were already sitting empty. There was no Senate-confirmed U.S. surgeon general . The head of the National Institutes of Health was doubling as the acting head of the U.S. Centers for Disease Control and Prevention. The Food and Drug Administration lacked a permanent vaccine chief after that official was ousted for a second time in a year. Then on Tuesday Dr. Marty Makary resigned