Regional blocs have called for restraint, while flights are suspended African nations and regional blocs have responded to the escalation of the conflict in the Middle East, after US-Israeli strikes killed Iranian Supreme Leader Ayatollah Ali Khamenei and other senior Iranian figures, as well as hundreds of civilians, including more than 100 schoolgirls in a strike in the southern city of Minab. In retaliation, Iran has launched large waves of missile and drone strikes targeting Israel and US