Education One out of every three adults around the world will develop shingles — a reactivation of the varicella-zoster virus . The varicella-zoster virus is the same virus that causes chickenpox . Adults ages 50 and older can be vaccinated against shingles. The vaccine provides more than 90% protection against developing shingles. Past studies show that in addition to providing protection against shingles, the vaccine may also provide other health benefits, including a potentially lower risk