Lower force leads to faster cell movement on aligned collagen fibers

Mădălina Grigore

Washington University in St. Louis Jan 10 2025 In mechanobiology, cells' forces have been considered fundamental to their enhanced function, including fast migration. But a group of researchers in the McKelvey School of Engineering at Washington University in St. Louis has found that cells can generate and use lower force yet move faster than cells generating and using high forces, turning the age-old assumption of force on its head. The laboratory of Amit Pathak, professor of mechanical

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