New therapeutic target could boost CAR T-cell therapy success in solid tumors

Mădălina Grigore

Mass General Brigham Jan 10 2025 Russell W. Jenkins, MD, PhD, a physician investigator in the Krantz Family Center for Cancer Research at the Mass General Cancer Center and an assistant professor of Medicine at Harvard Medical School, is senior author of a new study in Cancer Immunology Research, "TBK1 is Identified as a Therapeutic Strategy to Enhance CAR T-Cell Efficacy Using Patient-Derived Organotypic Tumor Spheroids". The study was a collaboration with the late Soldano Ferrone, MD, PhD,