By Dr. Liji Thomas, MD Reviewed by Lauren Hardaker Mar 31 2026 A sweeping analysis of global evidence suggests nicotine e-cigarettes may outperform traditional quit aids, but lingering safety uncertainties and research gaps keep the debate far from settled. Study: Electronic cigarettes for smoking cessation: An overview of systematic reviews and evidence and gap map . Image credit: StockLab/Shutterstock.com  Electronic cigarettes, or vapes, are often offered to help people quit the smoking