The world record for most time spent in space is held by Russian cosmonaut and Hero of Russia Oleg Kononenko, who has spent 1,110 days, 14 hours, 57 minutes in space over five missions MOSCOW, April 11. /TASS/. In recorded history, 631 people from 43 countries have journeyed to outer space, including 82 women from 13 nations. These figures include professional space travelers, non-professional astronauts, and space tourists. The United States has sent the most astronauts to space (369 people).