UT Southwestern researchers discovered that the HELZ2 protein regulates apolipoprotein B (APOB), a gene essential for forming lipoproteins that transport cholesterol and fat through the blood. In these images, aortic root sections from mice lacking the LDL receptor (LDLR) and carrying the HELZ2 mutation (right) show reduced atherosclerotic plaque (red) compared with LDLR-deficient controls (left). Credit: UT Southwestern Medical Center Researchers at UT Southwestern Medical Center have