University at Buffalo Mar 31 2026 When cells experience enough chronic stress, they can stop dividing permanently. In this state of cellular limbo, known as replicative senescence, cells remain alive but no longer proliferate. Pinpointing the stressors that help trigger or accelerate replicative senescence has proven difficult.  Now, in a study to be published March 30 in Cell Chemical Biology, University at Buffalo scientists have shed light on one such stressor - showing that an impaired