Ann & Robert H. Lurie Children's Hospital of Chicago Sep 18 2025 A new clinical trial has revealed encouraging results for a muscle-targeting therapy aimed at improving motor function in children and adolescents with spinal muscular atrophy, according to a study published in  The Lancet Neurology.   Spinal muscular atrophy (SMA) is a rare genetic disorder that affects motor neurons - nerve cells in the spinal cord responsible for controlling voluntary muscle movement. Caused by mutations in the