New method reveals how mitochondrial DNA mutations influence cancer growth
Mihaela Măncilă
St. Jude Children's Research Hospital Sep 10 2025 Mitochondria act as energy factories in cells and have their own, separate DNA. Mutations to mitochondrial DNA (mtDNA) have been observed in cancer, but it has been unclear how these changes might affect cancer growth. To find answers, St. Jude Children's Research Hospital scientists combined computational tools and DNA sequencing technologies to examine these mtDNA mutations in cancer cells closely. Their new method lets scientists pinpoint
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